Architect, partner of the architectural bureau Nowadays Office, member of Union of Moscow Architects. In 2006, graduated from Samara State Technical University (class of S. Malakhov and E. Repina). Wrote a study on the development of the system of public spaces in historic cities. Natalya Mastalerzh studied interior design at IED, Milano. She was a participant of the Architecture Biennale in Venice in 2004 and the 2nd International Architecture Biennale Rotterdam (The Flood). 2006–2011 — worked at the architectural bureau Meganom.
In 2013, she became a partner at Nowadays. In 2017, she held a MARCH-Lab workshop dedicated to the architectural renovation of the Houses of Culture in Tatarstan. 2018–2019 — Natalya Mastalerzh and Nata Tatunashvili taught the design programme Moscow's Peculiarities for graduate students at MARCH Architectural School.